By way of the Ten Thousand Year Blog: The Library of Congress has announced the availability of a Premis in METS Toolbox.
The PREMIS in METS Toolbox is a set of open-source tools developed to support the implementation of PREMIS in the METS container format. The tools were created by Florida Center for Library Automation for the Library of Congress in 2009.
The toolbox’s Describe module uses JHOVE for format characterization.
Mad File Format Science 